About the PhD Course

The PhD entails specific commitment and training in the following areas:

1. Experimental research

• Vascular biology with emphasis on the endothelium and endothelial (dys)function, and its role in the control of vascular tone;
• Salt and water homeostasis;
• Pathophysiology of control of blood pressure;
• Molecular analysis methodologies;
• Experimental atherosclerosis;
• Arterial hypertension from animal models;
• Molecular and experimental pharmacology;
• Pharmacokinetics and pharmacodynamics of anti-hypertensive medications.

2. Clinical research

• Epidemiology and statistics applied to hypertension;
• Principles of pharmaco-economics applied to hypertension;
• Methodologies for assessment of target organ damage in hypertension;
• Pathophysiology of the secondary forms of hypertension;
• Guidelines for risk stratification and treatment;
• Design and planning of clinical trials in hypertension.

  Curriculum

The First Year of Research

The student will do coursework and labwork.

The curriculum will involve:

1. General research methods training. An introductory course is held every year at the Venetian Institute of Medicine (VIMM) by the Faculty members of all PhD Courses of the University of Padua and outside experts in scientific fields. The course is focused on ‘How to do research” and covers applications of chemistry and physics to Medicine, genetics, molecular biology, statistics, ethics and social aspects.
2. Attendance at research workshops and seminars held by the Faculty members and PhD students or outside speakers, mostly focussed on the cardiovascular system.
3. Advanced coursework in the laboratories. The PhD student has the chance to be educated at a variety of techniques and introduced to a wide array of inter-disciplinary and comprehensive cardiovascular disease programs.

At the end of the 1st year the PhD student is expected to have practised skills of organizing, structuring, and presenting research,  Hence, he/she will be assigned to a specific research project in the field of Arterial Hypertension and Vascular biology under the strict supervision of an experienced tutor. Whether 1st year PhD student is upgraded to PhD status at the end of the first year of research will depend on his/her performance in the curriculum.

Second and Third Year of Research

Once upgraded to the 2nd year PhD student status, the student will concentrate on his/her PhD labwork to prepare his/her final dissertation. As research progresses, there will be opportunities to present work in progress at research workshops attended by Faculty members and research students. The PhD student will have also the opportunity to attend Journal Club and the Weekly Meetings given by outside speakers and Faculty members.

At the 2^nd or the 3^rd year the PhD student will spend at least 6 months abroad, at research organisations and universities collaborating with the PhD course.

The normal deadline for submission of the dissertation will be the end of December in the third year of research. Within this time, an original work focussed on the assigned theme should have been completed and discussed in detail with the tutor. The defence will occur about 2 months after, at the presence of the Faculty members.

  Application and Admission

To apply for the XLI Cycle to the PhD program in Arterial Hypertension and Vascular Biology, please follow this link: https://www.uniroma1.it/it/pagina/ammissione-ai-corsi-di-dottorato. For English version: https://www.uniroma1.it/en/pagina/admissions-2025-2026-phd-programmes.

Be aware also who's going to apply for the teaching site of the University of Padua, will apply through the call by University la Sapienza.

  Coordinator and Faculty Staff

Coordinator

Teresa M. Seccia, University of Padua, I

Faculty Staff

Giovanna Albertin, University of Padua, I 

Stefania Brozzetti, University of Rome La Sapienza, I 

Daniela Carnevale, University of Rome La Sapienza, I

Silvia Ceccanti, University of Rome La Sapienza, I

Giulio Ceolotto, University of Padua, I

Cristina Chimenti, University of Rome La Sapienza, I

Andrea Cignarella, University of Padua, I 

Denis A. Cozzi, University of Rome La Sapienza, I

Filippo Crimì, University of Padua, I

Giancarlo D'ambrosio, University of Rome La Sapienza, I

Carolina De Ciuceis, University of Brescia, I

Franco Grego, University of Padua, I

Maurizio Iacobone, University of Padua, I

Giuseppe Lembo, University of Rome La Sapienza, I

Claudio Letizia, University of Rome La Sapienza, I 

Stefano Masi, University of Pisa, I

Mirko Menegolo, University of Padua, I

Gianluca Mennini, University of Rome La Sapienza, I

Selenia Miglietta, University of Rome La Sapienza, I

Raffaella Motta, University of Padua, I

Maria Lorenza Muiesan, University of Brescia, I

Elena Pacella, University of Rome La Sapienza, I

Andrea Padoan, University of Padua, I

Luigi Petramala, University of Rome La Sapienza, I

Stefano Piaserico, University of Padua, I

Gianfranco Piccirillo, University of Rome La Sapienza, I

Giacomo Pucci, University of Perugia, I

Marcello Rattazzi, University of Padua, I 

Michela Relucenti, University of Rome La Sapienza, I

Massimo Rossi, University of Rome La Sapienza, I

Giacomo Rossitto, University of Padua, I

Massino Salvetti, University of Brescia, I

Susanna Sciomer, University of Rome La Sapienza, I

Roberto Stramare, University of Padua, I

Giuliano Tocci, University of Rome La Sapienza, I

Danilo Toni, University of Rome La Sapienza, I

Matthias Barton, University of Zurich, CH

Ariela Benigni, Istituto Mario Negri, I

Ana Briones Alonso, Universidad Autonoma de Madrid, E

Jan Danser, EUR Erasmus University Rotterdam, NL

Christian Delles, University of glasgow, UK

Tilman Hackeng, CARIM, NL

Abraham Kroon, CARIM, NL

Francesca Mallamaci, CNR, I

Marko Poglitsch, Attoquant Diagnostics, A

Koen Reesink, Maastricht University, NL

Leon Schurgers, CARIM, NL

Ulrike Muscha Steckelings, Syddansk Universitet, DN

Maria Christina Zennaro, INSERM, F

  PhD Students

Cycle XXVIII

Gioco Francesca

Guerzoni Eugenia

Pengo Martino

_____________________________________________________

Cycle XXIX

Citton Marilina

Ravarotto Verdiana

Vanderriele Paul Emmanuel

Viel Giovanni

___________________________________________________

Cycle XXXII

Scarpa Riccardo

Bisogni Valeria

Prisco Selene

Citoni Barbara

Torresan Francesca

Piazza Maria

Saracino Vincenza

___________________________________________________

Cycle XXXIII

Calvez Valentin

Cesario Vincenzo 

Concistrè Antonio 

Crimì Filippo

Miceli Francesca

Zingaretti Viviana

___________________________________________________

Cycle XXXIV

Caputo Ilaria

Nicolini Ettore

Presta Vivianne

Schiavone Donatella

Shagjaa Tungalagtamir

Zhu RUI

___________________________________________________

Cycle XXXV

Adducci Carmen

Alfarano Maria

Bressan Alessandro

Duraku Muja Eva

Figliuzzi Ilaria

Letteri Federica

Pata Francesco

Risitano Angela

Sanga Viola

Spimpolo Alessandro

Tartaglione Lida

__________________________________________________

Cycle XXXVI

Ajjour Hala

Byiringiro Clement

Circosta Francesco

Giovanardi Francesco

Mariani Marco Valerio

Neccia Matteo 

Petraglia Luca

Tini Melato Giacomo

__________________________________________________

Cycle XXXVII

Bagordo Domenico

Kohlscheen Eva

Pintus Giovanni

Zanon Chiara

__________________________________________________

Cycle XXXVIII

Bertoli Eleonora

Cabrelle Giulio

Costanzo Maria Ludovica

Scoccia Gianmarco

Zanella Luca

__________________________________________________

Cycle XXXIX

Catalfamo Marta

Khatoon Narjis

Mustafa Atta Ul

Poretto Anna

Rossi Federico

__________________________________________________

Cycle XL

Agostini Elena

Costantino Jacopo

D'alessandro Carlo

Marchionni Giulia

Myftari Vincenzo

Rizzo Massimiliano

Sammarco Ambra

Talli Ilaria

Tomarelli Elisa

  Activities

Weekly Meetings

The Weekly Meetings (open only to faculty and PhD students) are held every Wednesday at 08:15 a.m. During the meeting each PhD student will discuss his/her project and share the ongoing results with the Faculty members and other PhD students.

• 08/01/2025 update and discussion of the PhD student (Bagordo Domenico)
• 15/01/2025 update and discussion of the PhD student (Zanon Chiara)
• 29/01/2025 update and discussion of the PhD student (Khatoon Narjis)
• 05/02/2025 update and discussion of the PhD student (Cabrelle Giulio)
• 12/02/2025 update and discussion of the PhD student (Talli Ilaria)
• 19/02/2025 update and discussion of the PhD student (Mustafa Atta UI)
• 26/02/2025 update and discussion of the PhD student (Sammarco Ambra)
• 05/03/2025 update and discussion of the PhD student (Agostini Elena)
• 02/04/2025 update and discussion of the PhD student (Poretto Anna)
• 09/04/2025 update and discussion of the PhD student (Zanon Chiara)
• 16/04/2025 update and discussion of the PhD student (Khatoon Narjis)
• 30/04/2025 update and discussion of the PhD student (Talli Ilaria)
• 07/05/2025 update and discussion of the PhD student (Sammarco Ambra)
• 14/05/2025 update and discussion of the PhD student (Agostini Elena)
• 28/05/2025 update and discussion of the PhD student (Khatoon Narjis)

Journal Club

The Journal Club are held every Friday at 08:15 a.m. and are open to attendees. At each Journal Club recent papers focussed on experimental or clinical aspects of hypertension or cardiovascular diseases at large are presented by a PhD student and counter-discussed by another PhD student under the supervision of the Coordinator or another Faculty member.

• 10/01/2025 Relationship Between Renin, Aldosterone, Aldosterone-to-Renin Ratio and Arterial Stiffness and Left Ventricular Mass Index in Young Adults
• 24/01/2025 Characterizing the Origins of Primary Aldosteronism
• 31/01/2025 Circulating miRNAs and Machine Learning for Lateralizing Primary Aldosteronism
• 07/02/2025 Adrenomedullin 2/Intermedin Exerts Cardioprotective Effects by Regulating Cardiomyocyte Mitochondrial Function
• 14/02/2025 Modulation of Calcium Signaling on Demand to Decipher the Molecular Mechanisms of Primary Aldosteronism
• 21/02/2025 Persistent effect of salt reduction in schoolchildren and their families: 1-year follow-up after an application-based cluster randomized controlled trial
• 07/03/2025 In Vivo Dynamic and Static Analysis of Lymphatic Dysfunction in Lymphedema Using Near-Infrared Fluorescence Indocyanine Green Lymphangiography
• 14/03/2025 Clinical Utility of Dual‐Time 68Ga‐Pentixafor PET/CT in Diagnosing and Subtyping Primary Aldosteronism
• 21/03/2025 Endoscopic, ultrasound-guided, radiofrequency ablation of aldosterone-producing adenomas (FABULAS): a UK, multicentre, prospective, proof-of-concept trial
• 04/04/2025 Steroidomics-Based Screening for Primary Aldosteronism: Impact of antihypertensive Drugs
• 11/04/2025 Discussion on our unpublished research group's data
• 09/05/2025 NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury
• 16/05/2025 Discussion on our unpublished research group's data
• 23/05/2025 Discussion on our unpublished research group's data
• 30/05/2025 Nationwide, Pragmatic, Direct-to-Patient Primary Aldosteronism Testing Program

  Classrooms 2025

Advanced Laboratory Medicine

Dr. Ada Aita, Dr Paola Galozzi

From Mon. 03/02/2025 to 10/03/2025

Aula/room CASTELLINO - (Ground floor PAL. AMBULATORI)

 

Methodologies for Histological and Cytological Data: From Sampling to laboratory Research

Prof. Giovanna Albertin

02/04/2025 h. 16.00 / 17.30 Aula/room TERNI (IST. ANATOMIA)

09/04/2025 h. 16.00 / 17.30 Aula/room TERNI (IST. ANATOMIA)

16/04/2025 h. 16.00 / 17.30 Aula/room B - 8th Floor POLICLINICO

 

Clinical genetics

Prof. Eva Trevisson

29/04/2025 h. 16.00 / 18.00 Aula/room E - (Clinica dermosifilopatica - V. Gallucci)

12/05/2025 h. 16.00 / 18.00 Aula/room E - (Clinica dermosifilopatica - V. Gallucci) 

 

Effective Communication skills

Prof. M. Grazia Busà

13/05/2025 h. 14.00 /17.00 Aula/room E - (Clinica dermosifilopatica - V. Gallucci)

 

Scientific Communication, Open Science and the Institutional Archives

Dr. Valentina Bozzato, Dr. Federico Fogo, Dr. Antonia Villa

17/06/2025 h. 15.30 / 17.30 Aula/room B - 8th Floor POLICLINICO

24/06/2025 h. 16.00 / 17.00 Aula/room B - 8th Floor POLICLINICO

01/07/2025 h. 16.00 / 18.00 Aula/room B - 8th Floor POLICLINICO

 

Biostatistics

Prof. D. Gregori

From 06/05/2025 to 27/05/2025

Date and place to be confirmed

  Recent Publications

Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing Adenoma, Letter to the Editor. Schiavone D, Iacobone M, Rossi GP. Journal of Clinical Hypertension - 2022. PMID: 34967112 - DOI: 10.1111/jch.14416

Identification of glucocorticoid-related molecular signature by whole blood methylome analysis. Armignacco R, Anne Jouinot A, Bouys L, Septier A, Lartigue T, Neou M, Gaspar C, Karine Perlemoine K, Braun L, Riester A, Bonnet-Serrano F, Blanchard A, Amar L, Scaroni C, Ceccato F, Rossi GP, Williams TA, Larsen C, Allassonnière S, Zennaro MC, Beuschlein F, Reincke M, Bertherat J, Assié G. European Journal of Endocrinology - 2022. PMID: 34914631 - DOI: 10.1530/EJE-21-0907

Feasibility of Imaging-Guided Adrenalectomy in Young Patients With Primary Aldosteronism. Rossi GP, Crimì F, Rossitto G, Amar L, Azizi M, Riester A, Reincke M, Degenhart C, Widimsky J, Naruse M, Deinum J, Schultze Kool L, Kocjan T, Negro A, Rossi E, Kline G, Tanabe A, Satoh F, Rump LS, Vonend O, Willenberg H, Fuller PJ, Yang J, Yong Nian Chee N, Magill SB, Shafigullina Z, Quinkler M, Oliveras A, Wu VC, Kratka Z, Barbiero G, Battistel M, Seccia TM. Hypertension - 2022. PMID: 34878892 - DOI: 10.1161/HYPERTENSIONAHA.121.18284

Modern Management of Hypertensive Emergencies. Rossi GP, Rossitto G, Maifredini C, Barchitta A, Bettella A, Cerruti L, Latella R, Ruzza L, Sabini B, Vigolo, Seccia TM. High Blood Pressure & Cardiovascular Prevention - 2022. PMID: 34813055 - DOI: 10.1007/s40292-021-00487-1

Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism, Letter to the Editor. Rossi GP, Rossitto G. Journal of Clinical Endocrinology & Metabolism - 2022. PMID: 34610120 - DOI: 10.1210/clinem/dgab717

Neuropeptide G Protein-Coupled Receptor Regulation of Adrenal Function: Bench to Bedside and Back. Lenzini L, Caroccia B, Seccia TM, Rossi GP. Endocrine Reviews - 2022. PMID: 35436330 - DOI: 10.1210/endrev/bnac011 

Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells. Caputo I, Caroccia B, Frasson I, Poggio E, Zamberlan S, Morpurgo M, Seccia TM, Calì T, Brini M, Richter SN, Rossi GP. International Journal Of Molecular Sciences - 2022. PMID: 35563515 - DOI: 10.3390/ijms23095125

Management and Outcomes of Primary Aldosteronism in Pregnancy: A Systematic Review. Sanga V, Rossitto G, Seccia TM, Rossi GP. Hypertension - 2022. PMID: 35686552 - DOI: 10.1161/HYPERTENSIONAHA.121.18858

Aldosterone and Cardiovascular Damage: a New Lesson From an Old Study. Rossi GP, Rossitto G. Hypertension - 2022. PMID: 35947644 - DOI: 10.1161/HYPERTENSIONAHA.122.19662 

Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma. Pommer G, Pamporaki C, Peitzsch M, Remde H, Deutschbein T, Nölting S, Müller LM, Braun L, Gruber S, Pecori A, Hampson S, Davies E, Stell A, Rossi GP, Lenzini L, Ceccato F, Timmers HJLM, Deinum J, Amar L, Blanchard A, Baron S, Fassnacht M, Dobrowolski P, Januszewicz A, Zennaro MC, Prejbisz A, Eisenhofer G. Journal of Clinical Endocrinology & Metabolism - 2022. PMID: 35767279  - DOI: 10.1210/clinem/dgac390

Predicting Hypertension Subtypes with Machine Learning Using Targeted Metabolites and Their Ratios. Reel S, Reel PS, Erlic Z, Amar L, Pecori A, Larsen CK, Tetti M, Pamporaki C, Prehn C, Adamski J, Prejbisz A, Ceccato F, Scaroni C, Kroiss M, Dennedy MC, Deinum J, Eisenhofer G, Langton K, Mulatero P, Reincke M, Rossi GP, Lenzini L, Davies E, Gimenez-Roqueplo AP, Assié G, Blanchard A, Zennaro MC, Beuschlein F, Jefferson ER. Metabolites - 2022. PMID: 36005627 - DOI: 10.3390/metabo1208075 

Identification of risk loci for primary aldosteronism in genome-wide association studies. Le Floch E, Cosentino T, Larsen CK, Beuschlein F, Reincke M, Amar L, Rossi GP, De Sousa K, Baron S, Chantalat S, Saintpierre B, Lenzini L, Frouin A, Giscos-Douriez I, Ferey M, Abdellatif AB, Meatchi T, Empana JP, Jouven X, Gieger C, Waldenberger M, Peters A, Cusi D, Salvi E, Meneton P, Touvier M, Deschasaux M, Druesne-Pecollo N, Boulkroun S, Fernandes-Rosa FL, Deleuze JF, Jeunemaitre X, Zennaro MC. Nature Communications - 2022. PMID: 36057693 - DOI: 10.1038/s41467-022-32896-8

Challenges in the evaluation of endothelial cell dysfunction: a statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors. Rossi GP, Barton M, Dhaunc N, Rizzoni D, Seccia TM.  Journal of Hypertension - 2022 DOI:10.1097/HJH.0000000000003314

Whole blood methylome-derived features to discriminate endocrine hypertension. Armignacco R, Reel PS, Reel S, Jouinot A, Septier A, Gaspar C, Perlemoine K, Larsen CK, Bouys L, Braun L, Riester A, Kroiss M, Bonnet-Serrano F, Amar L, Blanchard A, Gimenez-Roqueplo AP, Prejbisz A, Januszewicz A, Dobrowolski P, Davies E, MacKenzie SM, Rossi GP, Lenzini L, Ceccato F, Scaroni C, Mulatero P, Williams TA, Pecori A, Monticone S, Beuschlein F, Reincke M, Zennaro MC, Bertherat J, Jefferson E, Assié G. Clinical Epigenetics - 2022. PMID: 36329530 - DOI: 10.1186/s13148-022-01347-y

Machine learning for classification of hypertension subtypes using multi-omics: A multi-centre, retrospective, data-driven study. Reel PS, Reel S, van Kralingen JC, Langton K, Lang K, Erlic Z, Larsen CK, Amar L, Pamporaki C, Mulatero P, Blanchard A, Kabat M, Robertson S, MacKenzie SM, Taylor AE, Peitzsch M, Ceccato F, Scaroni C, Reincke M, Kroiss M, Dennedy MC, Pecori A, Monticone S, Deinum J, Rossi GP, Lenzini L, McClure JD, Nind T, Riddell A, Stell A, Cole C, Sudano I, Prehn C, Adamski J, Gimenez-Roqueplo AP, Assié G, Arlt W, Beuschlein F, Eisenhofer G, Davies E, Zennaro MC, Jefferson E. Ebiomedicine - 2022. PMID: 36179553 - DOI: 10.1016/j.ebiom.2022.104276

Peptidergic G Protein-Coupled Receptor Regulation of Adrenal Function: Bench to Bedside and Back. Lenzini L, Caroccia B, Seccia TM, Rossi GP. Endocrine Reviews - 2022. PMID: 35436330 - DOI: 10.1210/endrev/bnac011

Serum levels of autoantibodies against the angiotensin II type I receptor are not associated with serum dicarbonyl or AGE levels in patients with an aldosterone-producing adenoma. Piazza M, Hanssen NMJ, Scheijen JLJM, Vd Waarenburg M, Caroccia B, Seccia TM, Stehouwer CDA, Rossi GP, Schalkwijk CG. Journal of Human Hypertension - 2022. PMID: 36418426 - DOI: 10.1038/s41371-022-00773-y 

Skin Hyperpigmentation Due to Post-Surgical Adrenal Insufficiency Regressed with the Dexamethasone Treatment. Shagjaa T, Sanga V, Rossi GP. Journal of Clinical Medicine - 2022. PMID: 36143026 - DOI: 10.3390/jcm11185379

Identification of Surgically Curable Primary Aldosteronism by Imaging in a Large, Multiethnic International Study. Rossi GP, Crimì F, Rossitto G, Amar L, Azizi M, Riester A, Reincke M, Degenhart C, Widimsky J, Naruse M, Jaap Deinum J, Schultze Kool L, Kocjan T, Negro A, Rossi E, Kline G, Tanabe A, Satoh F, Rump LC, Vonend O, Willenberg HS, Fuller PJ, Yang J, Yong Nian Chee N, Magill S, Shafigullina Z, Quinkler M, Oliveras A, Cent Wu V, Kratka Z, Barbiero G, Seccia TM, Battistel M. Journal of Clinical Endocrinology & Metabolism - 2021. PMID: 34212188 - DOI: 10.1210/clinem/dgab482       

Comparison of Cortisol, Androstenedione and Metanephrines to Assess Selectivity and Lateralization of Adrenal Vein Sampling in Primary Aldosteronism. Ceolotto G, Antonelli G, Caroccia B, Battistel M, Barbiero G, Plebani M, Rossi GP. Journal of Clinical Medicine - 2021. PMID: 34682878 - DOI: 10.3390/jcm10204755

Effects of insomnia and restless legs syndrome on sleep arterial blood pressure: A systematic review and meta-analysis. Maiolino G, Bisogni V, Soranna D, Pengo M, Pucci G, Vettor R, Fava C, Colussi GL, Bilo G, Lombardi C, Parati G, Rossi GP, Silvani A. Sleep Disorders Working Group of the Italian Society of Hypertension. Sleep Medicine Reviews - 2021. PMID: 34044356 - DOI: 10.1016/j.smrv.2021.101497 

A systematic review of pathophysiology and management of familial hyperaldosteronism type 1 in pregnancy. Sanga V, Seccia TM, Rossi GP. Endocrine - 2021. PMID: 34043182 - DOI: 10.1007/s12020-021-02763-5

Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis, Letter to the Editor. Zhu R, Tungalagtamir S, Seccia TM, Rossi GP. Journal of Clinical Endocrinology & Metabolism - 2021. PMID: 34197581 - DOI: 10.1210/clinem/dgab485

Outcome of adrenal vein sampling and computed tomography guided adrenalectomy in primary aldosteronism. Crimì F, Torresan F, Iacobone M, Rossi GP. Journal of Hypertension - 2021. PMID: 34188009 - DOI: 10.1097/HJH.0000000000002882

Management of hypertensive emergencies: a practical approach. Rossi GP, Rossitto G, Maifredini C, Barchitta A, Bettella A, Latella R, Ruzza L, Sabini B, Seccia TM. Blood Pressure - 2021. PMID: 33966560 - DOI: 10.1080/08037051.2021.1917983

Aldosterone and Cortisol Synthesis Regulation by Angiotensin-(1-7) and ACE-2 in The Human Adrenal Cortex. Caroccia B, Vanderriele PE, Seccia TM, Piazza M, Lenzini L, Prisco S, Torresan F, Domenig O, Iacobone M, Poglitsch M, Rossi GP. Journal of Hypertension - 2021. PMID: 33657582 - DOI: 10.1097/HJH.0000000000002816

Reduced adrenal surgery in COVID-19 pandemic: a possible ticking time bomb. Schiavone D, Torresan F, Rossi GP, Iacobone M. British Journal of Surgery - 2021. PMID: 33842946 - DOI:10.1093/bjs/znab098

Ablation versus laparoscopic adrenalectomy for the treatment of aldosterone-producing adenoma: a meta-analysis. Letter to the editor. Schiavone D, Sanga V, Iacobone M, Rossi GP. Abdominal Radiology - 2021. PMID: 33624132 - DOI 10.1007/s00261-021-02995-z

Urinary sodium potassium ratio is associated with clinical success after adrenalectomy in patients with unilateral primary aldosteronism. Zhu R, Seccia TM, Rossi GP. Therapeutic Advances in Chronic Disease - 2021. PMID: 34178299 - DOI: 10.1177/20406223211022650 

The cardiovascular consequences of hyperaldosteronism. ROSSI GP, Seccia TM, Maiolino G, Cesari M. Annales d’Endocrinologie - 2021. PMID: 32192789 - DOI: 10.1016/j.ando.2020.02.006.

High sodium intake, glomerular hyperfiltration, and protein catabolism in patients with essential hypertension. Rossitto G, Maiolino G, Lerco S, Ceolotto G, Blackburn G, Mary S, Antonelli G, Berton C, Bisogni V, Cesari M, Seccia TM, Lenzini L, Pinato A, Montezano A, Touyz RM, Petrie MC, Daly R, Welsh P, Plebani M, Rossi GP, Delles C. Cardiovascular Research - 2021. PMID: 33053160 - DOI: 10.1093/cvr/cvaa205

Are microcatheters really necessary in adrenal vein sampling (AVS) in primary aldosteronism? Letter to the Editor. Crimi F, Torresan F, Rossi GP. British Journal of Radiology - 2021. PMID: 33684300 - DOI: 10.1259/bjr.20200387

Familial hyperaldosteronism type 1 in pregnancy: a happy end with low dose dexamethasone. Sanga V, Lenzini L, Seccia TM ROSSI GP. Blood Pressure - 2021. PMID: 33390031 - DOI: 10.1080/08037051.2020.1863771

Development and Validation of Criteria for Sparing Confirmatory Tests in Diagnosing Primary Aldosteronism. Letter to the Editor. Zhu R, Rossi GP. Journal of Clinical Endocrinology & Metabolism - 2021. PMID: 33125050 - DOI: 10.1210/clinem/dgaa787 

Functional imaging by 11C-metomidate PET: a really useless technique for primary aldosteronism subtyping? Crimì F, Spimpolo A, Cecchin D, Rossi GP. European Journal of Endocrinology - 2021. PMID: 33555270 - DOI: 10.1530/EJE-20-1402

The European/International Fibromuscular Dysplasia Registry and Initiative (FEIRI)-clinical phenotypes and their predictors based on a cohort of 1000 patients. Pappaccogli M, Di Monaco S, Warchoł-Celińska E, Lorthioir A, Amar L, Aparicio LS, Beauloye C, Bruno RM, Chenu P, de Leeuw P, De Backer T, Delmotte P, Dika Z, Gordin D, Heuten H, Iwashima Y, Krzesinski JM, Kroon AA, Mazzolai L, Poch E, Sarafidis P, Seinturier C, Spiering W, Toubiana L, Van der Niepen P, van Twist D, Visonà A, Wautrecht JC, Witowicz H, Xu J, Prejbisz A, Januszewicz A, Azizi M, Persu A. European/International FMD Registry and Initiative (FEIRI), and the Working Group ‘Hypertension and the Kidney’ of the European Society of Hypertension (ESH). Cardiovascular Research - 2021. PMID: 32282921 - DOI: 10.1093/cvr/cvaa102        

Aldosterone synthase inhibitors for cardiovascular diseases: a comprehensive review of preclinical, clinical and in silico data. Lenzini L, Zanotti G, Bonchio M, Rossi GP. Pharmacological Research - 2021. PMID: 33271294 - DOI: 10.1016/j.phrs.2020.105332

Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex. Caroccia B, Vanderriele PE, Seccia TM, Piazza M, Lenzini L, Prisco S, Torresan F, Domening O, Iacobone M, Poglitsch M, Rossi GP.J Hypertens. 2021 Mar 1. doi: 10.1097/HJH.0000000000002816. Online ahead of print.PMID: 33657582

The 2020 Italian Society of Arterial Hypertension (SIIA) practical guidelines for the management of primary aldosteronism. Rossi GP, Bisogni V, Bacca AV, Belfiore A, Cesari M, Concistrè A, Del Pinto R, Fabris B, Fallo F, Fava C, Ferri C, Giacchetti G, Grassi G, Letizia C, Maccario M, Mallamaci F, Maiolino G, Manfellotto D, Minuz P, Monticone S, Morganti A, Muiesan ML, Mulatero P, Negro A, Parati G, Pengo MF, Petramala L, Pizzolo F, Rizzoni D, Rossitto G, Veglio F, Seccia TM.Int J Cardiol Hypertens. 2020 Apr 15;5:100029. doi: 10.1016/j.ijchy.2020.100029. eCollection 2020 Jun.PMID: 33447758

Familial hyperaldosteronism type 1 and pregnancy: successful treatment with low dose dexamethasone. Sanga V, Lenzini L, Seccia TM, Rossi GP.Blood Press. 2021 Jan 4:1-5. doi: 10.1080/08037051.2020.1863771. Online ahead of print.PMID: 33390031

Aldosterone synthase inhibitors for cardiovascular diseases: A comprehensive review of preclinical, clinical and in silico data. Lenzini L, Zanotti G, Bonchio M, Rossi GP.Pharmacol Res. 2021 Jan;163:105332. doi: 10.1016/j.phrs.2020.105332. Epub 2020 Dec 1.PMID: 33271294.

Practice Recommendations for Diagnosis and Treatment of the Most Common Forms of Secondary Hypertension. Rossi GP, Bisogni V, Rossitto G, Maiolino G, Cesari M, Zhu R, Seccia TM.High Blood Press Cardiovasc Prev. 2020 Dec;27(6):547-560. doi: 10.1007/s40292-020-00415-9. Epub 2020 Nov 7.PMID: 33159664

High Sodium Intake, Glomerular Hyperfiltration and Protein Catabolism in Patients with Essential Hypertension. Rossitto G, Maiolino G, Lerco S, Ceolotto G, Blackburn G, Mary S, Antonelli G, Berton C, Bisogni V, Cesari M, Seccia TM, Lenzini L, Pinato A, Montezano A, Touyz RM, Petrie MC, Daly R, Welsh P, Plebani M, Rossi GP, Delles C.Cardiovasc Res. 2020 Jul 16:cvaa205. doi: 10.1093/cvr/cvaa205. Online ahead of print.PMID: 33053160

Primary aldosteronism in elderly, old, and very old patients. Cesari M, Seccia TM, Maiolino G, Rossi GP.J Hum Hypertens. 2020 Dec;34(12):807-813. doi: 10.1038/s41371-020-00395-2. Epub 2020 Sep 14.PMID: 32929132

Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension. Mulatero P, Monticone S, Deinum J, Amar L, Prejbisz A, Zennaro MC, Beuschlein F, Rossi GP, Nishikawa T, Morganti A, Seccia TM, Lin YH, Fallo F, Widimsky J.J Hypertens. 2020 Oct;38(10):1919-1928. doi: 10.1097/HJH.0000000000002510.PMID: 32890264

Resolution of drug-resistant hypertension by adrenal vein sampling-guided adrenalectomy: a proof-of-concept study. Torresan F, Rossitto G, Bisogni V, Lerco S, Maiolino G, Cesari M, Zhu R, Iacobone M, Seccia TM, Rossi GP.Clin Sci (Lond). 2020 Jun 12;134(11):1265-1278. doi: 10.1042/CS20200340.PMID: 32452518

Disease monitoring of Primary Aldosteronism. Rossi GP, Cesari M, Lenzini L, Seccia TM.Best Pract Res Clin Endocrinol Metab. 2020 Mar;34(2):101417. doi: 10.1016/j.beem.2020.101417. Epub 2020 Mar 10.PMID: 32336665.

Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension. Mulatero P, Monticone S, Deinum J, Amar L, Prejbisz A, Zennaro MC, Beuschlein F, Rossi GP, Nishikawa T, Morganti A, Seccia TM, Lin YH, Fallo F, Widimsky J.J Hypertens. 2020 Oct;38(10):1919-1928. doi: 10.1097/HJH.0000000000002510.PMID: 32890264

Disease monitoring of Primary Aldosteronism. Rossi GP, Cesari M, Lenzini L, Seccia TM.Best Pract Res Clin Endocrinol Metab. 2020 Mar;34(2):101417. doi: 10.1016/j.beem.2020.101417. Epub 2020 Mar 10.PMID: 32336665.

Vitamin D supplementation: a novel therapy for aldosteronism? Rossi GP, Lenzini L.Nat Rev Endocrinol. 2020 Jun;16(6):303-304. doi: 10.1038/s41574-020-0359-3.PMID: 32286517.

Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients. Rossi GP, Sanga V, Barton M.Elife. 2020 Apr 6;9:e57278. doi: 10.7554/eLife.57278.PMID: 32250244 

The cardiovascular consequences of hyperaldosteronism. Rossi GP, Seccia TM, Maiolino G, Cesari M.Ann Endocrinol (Paris). 2020 Feb 28:S0003-4266(20)30029-9. doi: 10.1016/j.ando.2020.02.006. Online ahead of print.PMID: 32192789

Effects of Mineralocorticoid and AT1 Receptor Antagonism on The Aldosterone-Renin Ratio In Primary Aldosteronism-the EMIRA Study. Rossi GP, Ceolotto G, Rossitto G, Maiolino G, Cesari M, Seccia TM.J Clin Endocrinol Metab. 2020 Jun 1;105(6):dgaa080. doi: 10.1210/clinem/dgaa080.PMID: 32067030

Atrial fibrillation as presenting sign of primary aldosteronism: results of the Prospective Appraisal on the Prevalence of Primary Aldosteronism in Hypertensive (PAPPHY) Study. Seccia TM, Letizia C, Muiesan ML, Lerco S, Cesari M, Bisogni V, Petramala L, Maiolino G, Volpin R, Rossi GP.J Hypertens. 2020 Feb;38(2):332-339. doi: 10.1097/HJH.0000000000002250.PMID: 31834121

Primary Aldosteronism: JACC State-of-the-Art Review. Rossi GP.J Am Coll Cardiol. 2019 Dec 3;74(22):2799-2811. doi: 10.1016/j.jacc.2019.09.057.PMID: 31779795.

Arterial Hypertension, Aldosterone, and Atrial Fibrillation. Seccia TM, Caroccia B, Maiolino G, Cesari M, Rossi GP.Curr Hypertens Rep. 2019 Nov 18;21(12):94. doi: 10.1007/s11906-019-1001-4.PMID: 31741119.

Heterogenous Responses to Cosyntropin in Primary Aldosteronism. Rossi GP.J Clin Endocrinol Metab. 2020 Mar 1;105(3):dgz133. doi: 10.1210/clinem/dgz133.PMID: 31665321 

Adrenal venous sampling in dye-allergic primary aldosteronism patients: prevalence, pitfalls and a possible solution. Battistel M, Ceolotto G, Barbiero G, Rossitto G, Rossi GP.J Hypertens. 2018 Sep;36(9):1942-1944. doi: 10.1097/HJH.0000000000001827.PMID: 30192309 

The Biology of Normal Zona Glomerulosa and Aldosterone-Producing Adenoma: Pathological Implications. Seccia TM, Caroccia B, Gomez-Sanchez EP, Gomez-Sanchez CE, Rossi GP.Endocr Rev. 2018 Dec 1;39(6):1029-1056. doi: 10.1210/er.2018-00060.PMID: 30007283 Review.

Does angiotensin II regulate parathyroid hormone secretion or not? Rossi GP, Prisco S.Clin Endocrinol (Oxf). 2018 Nov;89(5):568-569. doi: 10.1111/cen.13798. Epub 2018 Jul 11.PMID: 29947100 

Gitelman's Syndrome: characterization of a novel c.1181G>A point mutation and functional classification of the known mutations. Ravarotto V, Loffing J, Loffing-Cueni D, Heidemeyer M, Pagnin E, Calò LA, Rossi GP.Hypertens Res. 2018 Aug;41(8):578-588. doi: 10.1038/s41440-018-0061-1. Epub 2018 Jun 20.PMID: 29925901

Saga of Familial Hyperaldosteronism: Yet a New Channel. Lenzini L, Prisco S, Caroccia B, Rossi GP.Hypertension. 2018 Jun;71(6):1010-1014. doi: 10.1161/HYPERTENSIONAHA.118.11150. Epub 2018 May 7.PMID: 29735637 Review.

Mineralocorticoid receptor antagonists: time of repositioning them in the treatment of arterial hypertension. Rossi GP.J Hypertens. 2018 May;36(5):1015-1018. doi: 10.1097/HJH.0000000000001686.PMID: 29578956

Cure With Cryoablation of Arterial Hypertension Due to a Renin-Producing Tumor. Maiolino G, Battistel M, Barbiero G, Bisogni V, Rossi GP.Am J Hypertens. 2018 Apr 13;31(5):537-540. doi: 10.1093/ajh/hpx213.PMID: 29522074

Update in adrenal venous sampling for primary aldosteronism. Rossi GP.Curr Opin Endocrinol Diabetes Obes. 2018 Jun;25(3):160-171. doi: 10.1097/MED.0000000000000407.PMID: 29521660 Review.

Management of a Pregnant Woman With Fibromuscular Dysplasia. Berra E, Dominiczak AF, Touyz RM, Pierard S, Hammer F, Rossi GP, Micali RG, Staessen JA, Bursztyn M, Kahan T, Persu A.Hypertension. 2018 Apr;71(4):540-547. doi: 10.1161/HYPERTENSIONAHA.118.10819. Epub 2018 Feb 26.PMID: 29483231

Adrenalectomy Lowers Incident Atrial Fibrillation in Primary Aldosteronism Patients at Long Term. Rossi GP, Maiolino G, Flego A, Belfiore A, Bernini G, Fabris B, Ferri C, Giacchetti G, Letizia C, Maccario M, Mallamaci F, Muiesan ML, Mannelli M, Negro A, Palumbo G, Parenti G, Rossi E, Mantero F; PAPY Study Investigators.Hypertension. 2018 Apr;71(4):585-591. doi: 10.1161/HYPERTENSIONAHA.117.10596. Epub 2018 Feb 26.PMID: 29483224

Effect of Continuous Positive Airway Pressure on Blood Pressure Variability in Patients With Obstructive Sleep Apnea. Pengo MF, Ratneswaran C, Berry M, Kent BD, Kohler M, Rossi GP, Steier J.J Clin Hypertens (Greenwich). 2016 Nov;18(11):1180-1184. doi: 10.1111/jch.12845. Epub 2016 Jun 1.PMID: 27251875

Adrenal vein sampling versus CT scanning in primary aldosteronism. Funder JW, Rossi GP.Lancet Diabetes Endocrinol. 2016 Nov;4(11):886. doi: 10.1016/S2213-8587(16)30240-6.PMID: 27793316

Recent advances in the diagnosis and management of obstructive sleep apnea. Vianello A, Bisogni V, Rinaldo C, Gallan F, Maiolino G, Braccioni F, Guarda-Nardini L, Molena B, Rossi GP, Marchese-Ragona R; Padova Sleep Apnea Study Group.Minerva Med. 2016 Dec;107(6):437-451. Epub 2016 Sep 13.PMID: 27625198 Review.

Estrogen Signaling in the Adrenal Cortex: Implications for Blood Pressure Sex Differences. Caroccia B, Seccia TM, Barton M, Rossi GP.Hypertension. 2016 Oct;68(4):840-8. doi: 10.1161/HYPERTENSIONAHA.116.07660.PMID: 27600178 Review.

Metoclopramide unmasks potentially misleading contralateral suppression in patients undergoing adrenal vein sampling for primary aldosteronism. Rossitto G, Miotto D, Battistel M, Barbiero G, Maiolino G, Bisogni V, Sanga V, Rossi GP.J Hypertens. 2016 Nov;34(11):2258-65. doi: 10.1097/HJH.0000000000001082.PMID: 27512976

Obituary: Cesare Dal Palù MD 20-01-1923-18-01-2016. Pessina AC, Rossi GP.J Hypertens. 2016 May;34(5):1022. doi: 10.1097/hjh.0000000000000900.PMID: 27482560

Endothelin-1 Drives Epithelial-Mesenchymal Transition in Hypertensive Nephroangiosclerosis. Seccia TM, Caroccia B, Gioco F, Piazza M, Buccella V, Guidolin D, Guerzoni E, Montini B, Petrelli L, Pagnin E, Ravarotto V, Belloni AS, Calò LA, Rossi GP.J Am Heart Assoc. 2016 Jul 21;5(7):e003888. doi: 10.1161/JAHA.116.003888.PMID: 27444511 

Randomised sham-controlled trial of transcutaneous electrical stimulation in obstructive sleep apnoea. Pengo MF, Xiao S, Ratneswaran C, Reed K, Shah N, Chen T, Douiri A, Hart N, Luo Y, Rafferty GF, Rossi GP, Williams A, Polkey MI, Moxham J, Steier J.Thorax. 2016 Oct;71(10):923-31. doi: 10.1136/thoraxjnl-2016-208691. Epub 2016 Jul 19.PMID: 27435610 Clinical Trial.

Cardiac Remodeling in Patients With Primary and Secondary Aldosteronism: A Tissue Doppler Study. Cesari M, Letizia C, Angeli P, Sciomer S, Rosi S, Rossi GP.Circ Cardiovasc Imaging. 2016 Jun;9(6):e004815. doi: 10.1161/CIRCIMAGING.116.004815.PMID: 27307552

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2025 Winter School in Cardiovascular Medicine

PhD Program Arterial Hypertension and Vascular Biology (ARHYVAB). University of Padua.

The 2025 Winter School of the PhD Course in Arterial Hypertension and Vascular Biology (ARHYVAB) will take place in Bozen, from March 24th to 28th.

Correggere il DNA per curare le malattie genetiche del cuore

Prof. Silvia Priori

08/06/2025 h. 11.00 - Accademia Nazionale dei Lincei, Palazzo Corsini, Via della Lungara 10, Roma

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