PhD Program in Arterial Hypertension and Vascular Biology

The PhD program in Arterial Hypertension and Vascular Biology is based in the Department of Medicine – DIMED of the University of Padua.  This is a referral centre for Arterial Hypertension and cardiovascular diseases in Italy and a Centre of Excellence for Hypertension Research of the European Society of Hypertension (ESH).

This programme is the first in Europe devoted to Hypertension research and was established in conjunction with the University of Rome La Sapienza, Italy, and the School for Cardiovascular Diseases in Maastricht (CARIM), The Netherlands.  It requires a rotation across the three Universities and possibly stages at other leading research centres in Europe and the USA.

Università di Padova  https://www.unipd.it/dottoratoscheda/arhyvab

To apply for the XXXIX Cycle to the PhD program in Arterial Hypertension and Vascular Biology, please follow this link: https://phd.uniroma1.it/web/concorso39.aspx?i=3561&l=IT

which redirect to the main PhD call of the University La Sapienza of Rome.

  About the PhD Course

The PhD entails specific commitment and training in the following areas:

1. Experimental research

  • Vascular biology with emphasis on the endothelium and endothelial (dys)function, and its role in the control of vascular tone;
  • Salt and water homeostasis;
  • Pathophysiology of control of blood pressure;
  • Molecular analysis methodologies;
  • Experimental atherosclerosis;
  • Arterial hypertension from animal models;
  • Molecular and experimental pharmacology;
  • Pharmacokinetics and pharmacodynamics of anti-hypertensive medications.

2. Clinical research.

  • Epidemiology and statistics applied to hypertension;
  • Principles of pharmaco-economics applied to hypertension;
  • Methodologies for assessment of target organ damage in hypertension;
  • Pathophysiology of the secondary forms of hypertension;
  • Guidelines for risk stratification and treatment;
  • Design and planning of clinical trials in hypertension.

  Curriculum

The First Year of Research

The student will do coursework and labwork.

The curriculum will involve:

  1. General research methods training. An introductory course is held every year at the Venetian Institute of Medicine (VIMM) by the Faculty members of all PhD Courses of the University of Padua and outside experts in scientific fields. The course is focused on ‘How to do research” and covers applications of chemistry and physics to Medicine, genetics, molecular biology, statistics, ethics and social aspects.
  2. Attendance at research workshops and seminars held by the Faculty members and PhD students or outside speakers, mostly focussed on the cardiovascular system.
  3. Advanced coursework in the laboratories. The PhD student has the chance to be educated at a variety of techniques and introduced to a wide array of inter-disciplinary and comprehensive cardiovascular disease programs.

At the end of the 1st year the PhD student is expected to have practised skills of organizing, structuring, and presenting research,  Hence, he/she will be assigned to a specific research project in the field of Arterial Hypertension and Vascular biology under the strict supervision of an experienced tutor. Whether 1st year PhD student is upgraded to PhD status at the end of the first year of research will depend on his/her performance in the curriculum.

 

Second and Third Years of Research

Once upgraded to the 2nd year PhD student status, the student will concentrate on his/her PhD labwork to prepare his/her final dissertation. As research progresses, there will be opportunities to present work in progress at research workshops attended by Faculty members and research students. The PhD student will have also the opportunity to attend Journal Club and the Weekly Meetings given by outside speakers and Faculty members.

At the 2nd or the 3rd year the PhD student will spend at least 6 months abroad, at the CARIM or in another lab that could be of interest for the ongoing research.

The normal deadline for submission of the dissertation will be the end of December in the third year of research. Within this time, an original work focussed on the assigned theme should have been completed and discussed in detail with the tutor. The defence will occur about 2 months after, at the presence of the Faculty members, including members from CARIM.

  Application and Admission

Call for admission to the PhD Courses 39° Cycle 2023/2024 and enrollment procedure:

https://phd.uniroma1.it/web/concorso39.aspx?i=3561&l=IT

This link redirects to the Call of Università La Sapienza

 

 

  Coordinator and Faculty Staff

Coordinator

Gian Paolo Rossi

 

Faculty Staff

Giovanna Albertin, University of Padua, I 

Stefania Brozzetti, University of Rome La Sapienza, I 

Diego Cecchin, University of Padua, I

Giulio Ceolotto, University of Padua, I

Cristina Chimenti, University of Rome La Sapienza, I

Giancarlo D'ambrosio, University of Rome La Sapienza, I

Carolina De Ciuceis, University of Brescia, I

Franco Grego, University of Padua, I

Maurizio Iacobone, University of Padua, I

Claudio Letizia, University of Rome La Sapienza, I 

Sandro Mazzaferro, University of Rome La Sapienza, I

Mirko Menegolo, University of Padua, I

Gianluca Mennini, University of Rome La Sapienza, I

Raffaella Motta, University of Padua, I

Maria Lorenza Muiesan, University of Brescia, I

Elena Pacella, University of Rome La Sapienza, I

Andrea Padoan, University of Padua, I

Luigi Petramala, University of Rome La Sapienza, I

Stefano Piaserico, University of Padua, I

Gianfranco Piccirillo, University of Rome La Sapienza, I

Giacomo Pucci, University of Perugia, I

Marcello Rattazzi, University of Padua, I 

Michela Relucenti, University of Rome La Sapienza, I

Gian Paolo Rossi, University of Padua, I 

Massimo Rossi, University of Rome La Sapienza, I

Giacomo Rossitto, University of Padua, I

Massino Salvetti, University of Brescia, I

Susanna Sciomer, University of Rome La Sapienza, I

Teresa M. Seccia (Vice-Coordinator), University of Padua, I

Roberto Stramare, University of Padua, I

Giuliano Tocci, University of Rome La Sapienza, I

Danilo Toni, University of Rome La Sapienza, I

Matthias Barton, University of Zurich, CH

Ariela Benigni, Istituto Mario Negri, I

Ana Briones Alonso, Universidad Autonoma de Madrid, E

Christian Delles, University of glasgow, UK

Tilman Hackeng, CARIM, NL

Abraham Kroon, CARIM, NL

Francesca Mallamaci, CNR, I

Marko Poglitsch, Attoquant Diagnostics, A

Koen Reesink, Maastricht University, NL

Leon Schurgers, CARIM, NL

Ulrike Muscha Steckelings, Syddansk Universitet, DN

Maria Christina Zennaro, INSERM, F

 

  PhD Students

Cycle XXVIII

Francesca Gioco

Eugenia Guerzoni

Martino Pengo

_____________________________________________________

Cycle XXIX

Marilina Citton

Verdiana Ravarotto

Paul Emmanuel Vanderriele

Giovanni Viel

___________________________________________________

Cycle XXXII

Scarpa Riccardo

Bisogni Valeria

Prisco Selene

Citoni Barbara

Torresan Francesca

Piazza Maria

Saracino Vincenza

___________________________________________________

Cycle XXXIII

Calvez Valentin

Cesario Vincenzo 

Concistrè Antonio 

Crimì Filippo

Miceli Francesca

Zingaretti Viviana

___________________________________________________

Cycle XXXIV

Caputo Ilaria

Nicolini Ettore

Presta Vivianne

Schiavone Donatella

Shagjaa Tungalagtamir

Zhu RUI

___________________________________________________

Cycle XXXV

Adducci Carmen

Alfarano Maria

Bressan Alessandro

Duraku Muja Eva

Figliuzzi Ilaria

Letteri Federica

Pata Francesco

Risitano Angela

Sanga Viola

Spimpolo Alessandro

Tartaglione Lida

 __________________________________________________

Cycle XXXVI

Ajjour Hala

Byiringiro Clement

Circosta Francesco

Giovanardi Francesco

Mariani Marco Valerio

Neccia Matteo 

Petraglia Luca

Tini Melato Giacomo

 __________________________________________________

Cycle XXXVII

Bagordo Domenico

Kohlscheen Eva

Pintus Giovanni

Zanon Chiara

__________________________________________________

Cycle XXXVIII

Bertoli Eleonora

Cabrelle Giulio

Costanzo Maria Ludovica

Scoccia Gianmarco

Zanella Luca


Cycle XXXIX

Catalfamo Marta

Khatoon Narjis

Mustafa Atta Ul

Poretto Anna

Rossi Federico

  Activities


Weekly Meetings

 

The Weekly Meetings (open only to faculty and PhD students) are held every Wednesday at 08:15 a.m. During the meeting each PhD student will discuss his/her project and share the ongoing results with the Faculty members and other PhD students.

 

Journal Club

The Journal Club are held every Friday at 08:15 a.m. and are open to attendees. At each Journal Club recent papers focussed on experimental or clinical aspects of hypertension or cardiovascular diseases at large are presented by a PhD student and counter-discussed by another PhD student under the supervision of the Coordinator or another Faculty member.

  Recent Publications

Thirty-six-month results of laparoscopic-based renal denervation plus unilateral laparoscopic adrenalectomy for the treatment of patients with resistant hypertension caused by unilateral aldosterone-producing Adenoma, Letter to the Editor.

Schiavone D, Iacobone M, Rossi GPJournal of Clinical Hypertension - 2022. PMID: 34967112 - DOI: 10.1111/jch.14416 - IF: 3.738

 

Identification of glucocorticoid-related molecular signature by whole blood methylome analysis.

Armignacco R, Anne Jouinot A, Bouys L, Septier A, Lartigue T, Neou M, Gaspar C, Karine Perlemoine K, Braun L, Riester A, Bonnet-Serrano F, Blanchard A, Amar L, Scaroni C, Ceccato F, Rossi GP, Williams TA, Larsen C, Allassonnière S, Zennaro MC, Beuschlein F, Reincke M, Bertherat J, Assié G. European Journal of Endocrinology - 2022. PMID: 34914631 - DOI: 10.1530/EJE-21-0907 - IF: 6.664

 

Feasibility of Imaging-Guided Adrenalectomy in Young Patients With Primary Aldosteronism.

Rossi GP, Crimì F, Rossitto G, Amar L, Azizi M, Riester A, Reincke M, Degenhart C, Widimsky J, Naruse M, Deinum J, Schultze Kool L, Kocjan T, Negro A, Rossi E, Kline G, Tanabe A, Satoh F, Rump LS, Vonend O, Willenberg H, Fuller PJ, Yang J, Yong Nian Chee N, Magill SB, Shafigullina Z, Quinkler M, Oliveras A, Wu VC, Kratka Z, Barbiero G, Battistel M, Seccia TM. Hypertension - 2022. PMID: 34878892 - DOI: 10.1161/HYPERTENSIONAHA.121.18284 - IF: 10.190

 

Modern Management of Hypertensive Emergencies.

Rossi GP, Rossitto G, Maifredini C, Barchitta A, Bettella A, Cerruti L, Latella R, Ruzza L, Sabini B, Vigolo, Seccia TM. High Blood Pressure & Cardiovascular Prevention - 2022. PMID: 34813055 - DOI: 10.1007/s40292-021-00487-1

Mineralocorticoid Receptor Antagonist Effect on Aldosterone to Renin Ratio in Patients With Primary Aldosteronism, Letter to the Editor.

Rossi GP, Rossitto G. Journal of Clinical Endocrinology & Metabolism - 2022. PMID: 34610120 - DOI: 10.1210/clinem/dgab717 - IF: 5.958

 

Neuropeptide G Protein-Coupled Receptor Regulation of Adrenal Function: Bench to Bedside and Back.

Lenzini L, Caroccia B, Seccia TM, Rossi GP. Endocrine Reviews - 2022. PMID: 35436330 - DOI: 10.1210/endrev/bnac011 - IF: 19.871

 

Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells.

Caputo I, Caroccia B, Frasson I, Poggio E, Zamberlan S, Morpurgo M, Seccia TM, Calì T, Brini M, Richter SN, Rossi GP. International Journal Of Molecular Sciences - 2022. PMID: 35563515 - DOI: 10.3390/ijms23095125 - IF: 6.208

 

Management and Outcomes of Primary Aldosteronism in Pregnancy: A Systematic Review.

Sanga V, Rossitto G, Seccia TM, Rossi GP. Hypertension - 2022. PMID: 35686552 - DOI: 10.1161/HYPERTENSIONAHA.121.18858 - IF: 9.897

 

Aldosterone and Cardiovascular Damage: a New Lesson From an Old Study.

Rossi GP, Rossitto G. Hypertension - 2022. PMID: 35947644 - DOI: 10.1161/HYPERTENSIONAHA.122.19662 - IF: 9.897

 

Preanalytical Considerations and Outpatient Versus Inpatient Tests of Plasma Metanephrines to Diagnose Pheochromocytoma.

Pommer G, Pamporaki C, Peitzsch M, Remde H, Deutschbein T, Nölting S, Müller LM, Braun L, Gruber S, Pecori A, Hampson S, Davies E, Stell A, Rossi GP, Lenzini L, Ceccato F, Timmers HJLM, Deinum J, Amar L, Blanchard A, Baron S, Fassnacht M, Dobrowolski P, Januszewicz A, Zennaro MC, Prejbisz A, Eisenhofer G. Journal of Clinical Endocrinology & Metabolism - 2022. PMID: 35767279  - DOI: 10.1210/clinem/dgac390 – IF: 6.134

 

Predicting Hypertension Subtypes with Machine Learning Using Targeted Metabolites and Their Ratios.

Reel S, Reel PS, Erlic Z, Amar L, Pecori A, Larsen CK, Tetti M, Pamporaki C, Prehn C, Adamski J, Prejbisz A, Ceccato F, Scaroni C, Kroiss M, Dennedy MC, Deinum J, Eisenhofer G, Langton K, Mulatero P, Reincke M, Rossi GP, Lenzini L, Davies E, Gimenez-Roqueplo AP, Assié G, Blanchard A, Zennaro MC, Beuschlein F, Jefferson ER. Metabolites - 2022. PMID: 36005627 - DOI: 10.3390/metabo12080755 - IF: 5.581

 

Identification of risk loci for primary aldosteronism in genome-wide association studies.

Le Floch E, Cosentino T, Larsen CK, Beuschlein F, Reincke M, Amar L, Rossi GP, De Sousa K, Baron S, Chantalat S, Saintpierre B, Lenzini L, Frouin A, Giscos-Douriez I, Ferey M, Abdellatif AB, Meatchi T, Empana JP, Jouven X, Gieger C, Waldenberger M, Peters A, Cusi D, Salvi E, Meneton P, Touvier M, Deschasaux M, Druesne-Pecollo N, Boulkroun S, Fernandes-Rosa FL, Deleuze JF, Jeunemaitre X, Zennaro MC. Nature Communications - 2022. PMID: 36057693 - DOI: 10.1038/s41467-022-32896-8 - IF: 17.694

 

Challenges in the evaluation of endothelial cell dysfunction: a statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors.

Rossi GP, Barton M, Dhaunc N, Rizzoni D, Seccia TM.  Journal of Hypertension - 2022 DOI:10.1097/HJH.0000000000003314 - IF: 4.776

 

Whole blood methylome-derived features to discriminate endocrine hypertension.

Armignacco R, Reel PS, Reel S, Jouinot A, Septier A, Gaspar C, Perlemoine K, Larsen CK, Bouys L, Braun L, Riester A, Kroiss M, Bonnet-Serrano F, Amar L, Blanchard A, Gimenez-Roqueplo AP, Prejbisz A, Januszewicz A, Dobrowolski P, Davies E, MacKenzie SM, Rossi GP, Lenzini L, Ceccato F, Scaroni C, Mulatero P, Williams TA, Pecori A, Monticone S, Beuschlein F, Reincke M, Zennaro MC, Bertherat J, Jefferson E, Assié G. Clinical Epigenetics - 2022. PMID: 36329530 - DOI: 10.1186/s13148-022-01347-y - IF: 7.28

 

Machine learning for classification of hypertension subtypes using multi-omics: A multi-centre, retrospective, data-driven study.

Reel PS, Reel S, van Kralingen JC, Langton K, Lang K, Erlic Z, Larsen CK, Amar L, Pamporaki C, Mulatero P, Blanchard A, Kabat M, Robertson S, MacKenzie SM, Taylor AE, Peitzsch M, Ceccato F, Scaroni C, Reincke M, Kroiss M, Dennedy MC, Pecori A, Monticone S, Deinum J, Rossi GP, Lenzini L, McClure JD, Nind T, Riddell A, Stell A, Cole C, Sudano I, Prehn C, Adamski J, Gimenez-Roqueplo AP, Assié G, Arlt W, Beuschlein F, Eisenhofer G, Davies E, Zennaro MC, Jefferson E. Ebiomedicine - 2022. PMID: 36179553 - DOI: 10.1016/j.ebiom.2022.104276 - IF: 11.205

 

Peptidergic G Protein-Coupled Receptor Regulation of Adrenal Function: Bench to Bedside and Back.

Lenzini L, Caroccia B, Seccia TM, Rossi GP. Endocrine Reviews - 2022. PMID: 35436330 - DOI: 10.1210/endrev/bnac011 - IF: 25.261

 

Serum levels of autoantibodies against the angiotensin II type I receptor are not associated with serum dicarbonyl or AGE levels in patients with an aldosterone-producing adenoma.

Piazza M, Hanssen NMJ, Scheijen JLJM, Vd Waarenburg M, Caroccia B, Seccia TM, Stehouwer CDA, Rossi GP, Schalkwijk CG. Journal of Human Hypertension - 2022. PMID: 36418426 - DOI: 10.1038/s41371-022-00773-y - IF: 2.877

 

Skin Hyperpigmentation Due to Post-Surgical Adrenal Insufficiency Regressed with the Dexamethasone Treatment.

Shagjaa T, Sanga V, Rossi GP. Journal of Clinical Medicine - 2022. PMID: 36143026 - DOI: 10.3390/jcm11185379 - IF: 4.964

 

Identification of Surgically Curable Primary Aldosteronism by Imaging in a Large, Multiethnic International Study.

Rossi GP, Crimì F, Rossitto G, Amar L, Azizi M, Riester A, Reincke M, Degenhart C, Widimsky J, Naruse M, Jaap Deinum J, Schultze Kool L, Kocjan T, Negro A, Rossi E, Kline G, Tanabe A, Satoh F, Rump LC, Vonend O, Willenberg HS, Fuller PJ, Yang J, Yong Nian Chee N, Magill S, Shafigullina Z, Quinkler M, Oliveras A, Cent Wu V, Kratka Z, Barbiero G, Seccia TM, Battistel M. Journal of Clinical Endocrinology & Metabolism - 2021. PMID: 34212188 - DOI: 10.1210/clinem/dgab482 - IF: 6.134

           

Comparison of Cortisol, Androstenedione and Metanephrines to Assess Selectivity and Lateralization of Adrenal Vein Sampling in Primary Aldosteronism.

Ceolotto G, Antonelli G, Caroccia B, Battistel M, Barbiero G, Plebani M, Rossi GP. Journal of Clinical Medicine - 2021. PMID: 34682878 - DOI: 10.3390/jcm10204755 - IF: 4.964

  

Effects of insomnia and restless legs syndrome on sleep arterial blood pressure: A systematic review and meta-analysis.

Maiolino G, Bisogni V, Soranna D, Pengo M, Pucci G, Vettor R, Fava C, Colussi GL, Bilo G, Lombardi C, Parati G, Rossi GP, Silvani A. Sleep Disorders Working Group of the Italian Society of Hypertension. Sleep Medicine Reviews - 2021. PMID: 34044356 - DOI: 10.1016/j.smrv.2021.101497 - IF: 11.401

 

A systematic review of pathophysiology and management of familial hyperaldosteronism type 1 in pregnancy.

Sanga V, Seccia TM, Rossi GP. Endocrine - 2021. PMID: 34043182 - DOI: 10.1007/s12020-021-02763-5 - IF: 3.925

 

Performance of the Aldosterone-to-Renin Ratio as a Screening Test for Primary Aldosteronism: A Systematic Review and Meta-Analysis, Letter to the Editor.

Zhu R, Tungalagtamir S, Seccia TM, Rossi GP. Journal of Clinical Endocrinology & Metabolism - 2021. PMID: 34197581 - DOI: 10.1210/clinem/dgab485 - IF: 6.134

 

Outcome of adrenal vein sampling and computed tomography guided adrenalectomy in primary aldosteronism.

Crimì F, Torresan F, Iacobone M, Rossi GP. Journal of Hypertension - 2021. PMID: 34188009 - DOI: 10.1097/HJH.0000000000002882 – IF: 4.776

 

Management of hypertensive emergencies: a practical approach.

Rossi GP, Rossitto G, Maifredini C, Barchitta A, Bettella A, Latella R, Ruzza L, Sabini B, Seccia TM. Blood Pressure - 2021. PMID: 33966560 - DOI: 10.1080/08037051.2021.1917983 - IF: 1.771

 

Aldosterone and Cortisol Synthesis Regulation by Angiotensin-(1-7) and ACE-2 in The Human Adrenal Cortex.

Caroccia B, Vanderriele PE, Seccia TM, Piazza M, Lenzini L, Prisco S, Torresan F, Domenig O, Iacobone M, Poglitsch M, Rossi GP. Journal of Hypertension - 2021. PMID: 33657582 - DOI: 10.1097/HJH.0000000000002816 – IF: 4.776

 

Reduced adrenal surgery in COVID-19 pandemic: a possible ticking time bomb.

Schiavone D, Torresan F, Rossi GP, Iacobone M. British Journal of Surgery - 2021. PMID: 33842946 - DOI:10.1093/bjs/znab098 - IF: 11.782

 

Ablation versus laparoscopic adrenalectomy for the treatment of aldosterone-producing adenoma: a meta-analysis. Letter to the editor.

Schiavone D, Sanga V, Iacobone M, Rossi GP. Abdominal Radiology - 2021. PMID: 33624132 - DOI 10.1007/s00261-021-02995-z - IF: 2.886

 

Urinary sodium potassium ratio is associated with clinical success after adrenalectomy in patients with unilateral primary aldosteronism.

Zhu R, Seccia TM, Rossi GP. Therapeutic Advances in Chronic Disease - 2021. PMID: 34178299 - DOI: 10.1177/20406223211022650 - IF: 4.970

 

The cardiovascular consequences of hyperaldosteronism.

ROSSI GP, Seccia TM, Maiolino G, Cesari M. Annales d’Endocrinologie - 2021. PMID: 32192789 - DOI: 10.1016/j.ando.2020.02.006. - IF: 3.117

 

High sodium intake, glomerular hyperfiltration, and protein catabolism in patients with essential hypertension.

Rossitto G, Maiolino G, Lerco S, Ceolotto G, Blackburn G, Mary S, Antonelli G, Berton C, Bisogni V, Cesari M, Seccia TM, Lenzini L, Pinato A, Montezano A, Touyz RM, Petrie MC, Daly R, Welsh P, Plebani M, Rossi GP, Delles C. Cardiovascular Research - 2021. PMID: 33053160 - DOI: 10.1093/cvr/cvaa205 - IF: 14.239

 

Are microcatheters really necessary in adrenal vein sampling (AVS) in primary aldosteronism? Letter to the Editor.

Crimi F, Torresan F, Rossi GP. British Journal of Radiology - 2021. PMID: 33684300 - DOI: 10.1259/bjr.20200387 - IF: 3.629

 

Familial hyperaldosteronism type 1 in pregnancy: a happy end with low dose dexamethasone.

Sanga V, Lenzini L, Seccia TM ROSSI GP. Blood Pressure - 2021. PMID: 33390031 - DOI: 10.1080/08037051.2020.1863771 - IF: 1.771

 

Development and Validation of Criteria for Sparing Confirmatory Tests in Diagnosing Primary Aldosteronism. Letter to the Editor

Zhu R, Rossi GP. Journal of Clinical Endocrinology & Metabolism - 2021. PMID: 33125050 - DOI: 10.1210/clinem/dgaa787 - IF: 6.134

 

Functional imaging by 11C-metomidate PET: a really useless technique for primary aldosteronism subtyping?

Crimì F, Spimpolo A, Cecchin D, Rossi GP. European Journal of Endocrinology - 2021. PMID: 33555270 - DOI: 10.1530/EJE-20-1402 - IF: 6.558

 

The European/International Fibromuscular Dysplasia Registry and Initiative (FEIRI)-clinical phenotypes and their predictors based on a cohort of 1000 patients.

Pappaccogli M, Di Monaco S, Warchoł-Celińska E, Lorthioir A, Amar L, Aparicio LS, Beauloye C, Bruno RM, Chenu P, de Leeuw P, De Backer T, Delmotte P, Dika Z, Gordin D, Heuten H, Iwashima Y, Krzesinski JM, Kroon AA, Mazzolai L, Poch E, Sarafidis P, Seinturier C, Spiering W, Toubiana L, Van der Niepen P, van Twist D, Visonà A, Wautrecht JC, Witowicz H, Xu J, Prejbisz A, Januszewicz A, Azizi M, Persu A. European/International FMD Registry and Initiative (FEIRI), and the Working Group ‘Hypertension and the Kidney’ of the European Society of Hypertension (ESH). Cardiovascular Research - 2021. PMID: 32282921 - DOI: 10.1093/cvr/cvaa102 - IF: 14.239

           

Aldosterone synthase inhibitors for cardiovascular diseases: a comprehensive review of preclinical, clinical and in silico data.

Lenzini L, Zanotti G, Bonchio M, Rossi GP. Pharmacological Research - 2021. PMID: 33271294 - DOI: 10.1016/j.phrs.2020.105332 - IF: 10.334

 

Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex.

Caroccia B, Vanderriele PE, Seccia TM, Piazza M, Lenzini L, Prisco S, Torresan F, Domening O, Iacobone M, Poglitsch M, Rossi GP.J Hypertens. 2021 Mar 1. doi: 10.1097/HJH.0000000000002816. Online ahead of print.PMID: 33657582

 

The 2020 Italian Society of Arterial Hypertension (SIIA) practical guidelines for the management of primary aldosteronism.

Rossi GP, Bisogni V, Bacca AV, Belfiore A, Cesari M, Concistrè A, Del Pinto R, Fabris B, Fallo F, Fava C, Ferri C, Giacchetti G, Grassi G, Letizia C, Maccario M, Mallamaci F, Maiolino G, Manfellotto D, Minuz P, Monticone S, Morganti A, Muiesan ML, Mulatero P, Negro A, Parati G, Pengo MF, Petramala L, Pizzolo F, Rizzoni D, Rossitto G, Veglio F, Seccia TM.Int J Cardiol Hypertens. 2020 Apr 15;5:100029. doi: 10.1016/j.ijchy.2020.100029. eCollection 2020 Jun.PMID: 33447758 Free PMC article.

 

Familial hyperaldosteronism type 1 and pregnancy: successful treatment with low dose dexamethasone.

Sanga V, Lenzini L, Seccia TM, Rossi GP.Blood Press. 2021 Jan 4:1-5. doi: 10.1080/08037051.2020.1863771. Online ahead of print.PMID: 33390031

 

Aldosterone synthase inhibitors for cardiovascular diseases: A comprehensive review of preclinical, clinical and in silico data.

Lenzini L, Zanotti G, Bonchio M, Rossi GP.Pharmacol Res. 2021 Jan;163:105332. doi: 10.1016/j.phrs.2020.105332. Epub 2020 Dec 1.PMID: 33271294.

 

Practice Recommendations for Diagnosis and Treatment of the Most Common Forms of Secondary Hypertension.

Rossi GP, Bisogni V, Rossitto G, Maiolino G, Cesari M, Zhu R, Seccia TM.High Blood Press Cardiovasc Prev. 2020 Dec;27(6):547-560. doi: 10.1007/s40292-020-00415-9. Epub 2020 Nov 7.PMID: 33159664 Free PMC article.

 

High Sodium Intake, Glomerular Hyperfiltration and Protein Catabolism in Patients with Essential Hypertension.

Rossitto G, Maiolino G, Lerco S, Ceolotto G, Blackburn G, Mary S, Antonelli G, Berton C, Bisogni V, Cesari M, Seccia TM, Lenzini L, Pinato A, Montezano A, Touyz RM, Petrie MC, Daly R, Welsh P, Plebani M, Rossi GP, Delles C.Cardiovasc Res. 2020 Jul 16:cvaa205. doi: 10.1093/cvr/cvaa205. Online ahead of print.PMID: 33053160

 

Primary aldosteronism in elderly, old, and very old patients.

Cesari M, Seccia TM, Maiolino G, Rossi GP.J Hum Hypertens. 2020 Dec;34(12):807-813. doi: 10.1038/s41371-020-00395-2. Epub 2020 Sep 14.PMID: 32929132 .

 

Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension.

Mulatero P, Monticone S, Deinum J, Amar L, Prejbisz A, Zennaro MC, Beuschlein F, Rossi GP, Nishikawa T, Morganti A, Seccia TM, Lin YH, Fallo F, Widimsky J.J Hypertens. 2020 Oct;38(10):1919-1928. doi: 10.1097/HJH.0000000000002510.PMID: 32890264

 

Resolution of drug-resistant hypertension by adrenal vein sampling-guided adrenalectomy: a proof-of-concept study.

Torresan F, Rossitto G, Bisogni V, Lerco S, Maiolino G, Cesari M, Zhu R, Iacobone M, Seccia TM, Rossi GP.Clin Sci (Lond). 2020 Jun 12;134(11):1265-1278. doi: 10.1042/CS20200340.PMID: 32452518

 

Disease monitoring of Primary Aldosteronism.

Rossi GP, Cesari M, Lenzini L, Seccia TM.Best Pract Res Clin Endocrinol Metab. 2020 Mar;34(2):101417. doi: 10.1016/j.beem.2020.101417. Epub 2020 Mar 10.PMID: 32336665.

 

Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the Working Group on Endocrine Hypertension of The European Society of Hypertension.

Mulatero P, Monticone S, Deinum J, Amar L, Prejbisz A, Zennaro MC, Beuschlein F, Rossi GP, Nishikawa T, Morganti A, Seccia TM, Lin YH, Fallo F, Widimsky J.J Hypertens. 2020 Oct;38(10):1919-1928. doi: 10.1097/HJH.0000000000002510.PMID: 32890264

 

Disease monitoring of Primary Aldosteronism.

Rossi GP, Cesari M, Lenzini L, Seccia TM.Best Pract Res Clin Endocrinol Metab. 2020 Mar;34(2):101417. doi: 10.1016/j.beem.2020.101417. Epub 2020 Mar 10.PMID: 32336665.

 

Vitamin D supplementation: a novel therapy for aldosteronism?

Rossi GP, Lenzini L.Nat Rev Endocrinol. 2020 Jun;16(6):303-304. doi: 10.1038/s41574-020-0359-3.PMID: 32286517.

 

Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients.

Rossi GP, Sanga V, Barton M.Elife. 2020 Apr 6;9:e57278. doi: 10.7554/eLife.57278.PMID: 32250244 Free PMC article.

 

The cardiovascular consequences of hyperaldosteronism.

Rossi GP, Seccia TM, Maiolino G, Cesari M.Ann Endocrinol (Paris). 2020 Feb 28:S0003-4266(20)30029-9. doi: 10.1016/j.ando.2020.02.006. Online ahead of print.PMID: 32192789

 

Effects of Mineralocorticoid and AT1 Receptor Antagonism on The Aldosterone-Renin Ratio In Primary Aldosteronism-the EMIRA Study.

Rossi GP, Ceolotto G, Rossitto G, Maiolino G, Cesari M, Seccia TM.J Clin Endocrinol Metab. 2020 Jun 1;105(6):dgaa080. doi: 10.1210/clinem/dgaa080.PMID: 32067030

 

Atrial fibrillation as presenting sign of primary aldosteronism: results of the Prospective Appraisal on the Prevalence of Primary Aldosteronism in Hypertensive (PAPPHY) Study.

Seccia TM, Letizia C, Muiesan ML, Lerco S, Cesari M, Bisogni V, Petramala L, Maiolino G, Volpin R, Rossi GP.J Hypertens. 2020 Feb;38(2):332-339. doi: 10.1097/HJH.0000000000002250.PMID: 31834121

 

Primary Aldosteronism: JACC State-of-the-Art Review.

Rossi GP.J Am Coll Cardiol. 2019 Dec 3;74(22):2799-2811. doi: 10.1016/j.jacc.2019.09.057.PMID: 31779795.

 

Arterial Hypertension, Aldosterone, and Atrial Fibrillation.

Seccia TM, Caroccia B, Maiolino G, Cesari M, Rossi GP.Curr Hypertens Rep. 2019 Nov 18;21(12):94. doi: 10.1007/s11906-019-1001-4.PMID: 31741119.

 

Heterogenous Responses to Cosyntropin in Primary Aldosteronism.

Rossi GP.J Clin Endocrinol Metab. 2020 Mar 1;105(3):dgz133. doi: 10.1210/clinem/dgz133.PMID: 31665321 No abstract available.

 

Adrenal venous sampling in dye-allergic primary aldosteronism patients: prevalence, pitfalls and a possible solution.

Battistel M, Ceolotto G, Barbiero G, Rossitto G, Rossi GP.J Hypertens. 2018 Sep;36(9):1942-1944. doi: 10.1097/HJH.0000000000001827.PMID: 30192309 No abstract available.

 

The Biology of Normal Zona Glomerulosa and Aldosterone-Producing Adenoma: Pathological Implications.

Seccia TM, Caroccia B, Gomez-Sanchez EP, Gomez-Sanchez CE, Rossi GP.Endocr Rev. 2018 Dec 1;39(6):1029-1056. doi: 10.1210/er.2018-00060.PMID: 30007283 Free PMC article. Review.

 

Does angiotensin II regulate parathyroid hormone secretion or not?

Rossi GP, Prisco S.Clin Endocrinol (Oxf). 2018 Nov;89(5):568-569. doi: 10.1111/cen.13798. Epub 2018 Jul 11.PMID: 29947100 No abstract available.

 

Gitelman's Syndrome: characterization of a novel c.1181G>A point mutation and functional classification of the known mutations.

Ravarotto V, Loffing J, Loffing-Cueni D, Heidemeyer M, Pagnin E, Calò LA, Rossi GP.Hypertens Res. 2018 Aug;41(8):578-588. doi: 10.1038/s41440-018-0061-1. Epub 2018 Jun 20.PMID: 29925901

 

Saga of Familial Hyperaldosteronism: Yet a New Channel.

Lenzini L, Prisco S, Caroccia B, Rossi GP.Hypertension. 2018 Jun;71(6):1010-1014. doi: 10.1161/HYPERTENSIONAHA.118.11150. Epub 2018 May 7.PMID: 29735637 Review. No abstract available.

 

Mineralocorticoid receptor antagonists: time of repositioning them in the treatment of arterial hypertension.

Rossi GP.J Hypertens. 2018 May;36(5):1015-1018. doi: 10.1097/HJH.0000000000001686.PMID: 29578956 No abstract available.

 

Cure With Cryoablation of Arterial Hypertension Due to a Renin-Producing Tumor.

Maiolino G, Battistel M, Barbiero G, Bisogni V, Rossi GP.Am J Hypertens. 2018 Apr 13;31(5):537-540. doi: 10.1093/ajh/hpx213.PMID: 29522074

 

Update in adrenal venous sampling for primary aldosteronism.

Rossi GP.Curr Opin Endocrinol Diabetes Obes. 2018 Jun;25(3):160-171. doi: 10.1097/MED.0000000000000407.PMID: 29521660 Review.

 

Management of a Pregnant Woman With Fibromuscular Dysplasia.

Berra E, Dominiczak AF, Touyz RM, Pierard S, Hammer F, Rossi GP, Micali RG, Staessen JA, Bursztyn M, Kahan T, Persu A.Hypertension. 2018 Apr;71(4):540-547. doi: 10.1161/HYPERTENSIONAHA.118.10819. Epub 2018 Feb 26.PMID: 29483231 No abstract available.

 

Adrenalectomy Lowers Incident Atrial Fibrillation in Primary Aldosteronism Patients at Long Term.

Rossi GP, Maiolino G, Flego A, Belfiore A, Bernini G, Fabris B, Ferri C, Giacchetti G, Letizia C, Maccario M, Mallamaci F, Muiesan ML, Mannelli M, Negro A, Palumbo G, Parenti G, Rossi E, Mantero F; PAPY Study Investigators.Hypertension. 2018 Apr;71(4):585-591. doi: 10.1161/HYPERTENSIONAHA.117.10596. Epub 2018 Feb 26.PMID: 29483224

 

Effect of Continuous Positive Airway Pressure on Blood Pressure Variability in Patients With Obstructive Sleep Apnea.

Pengo MF, Ratneswaran C, Berry M, Kent BD, Kohler M, Rossi GP, Steier J.J Clin Hypertens (Greenwich). 2016 Nov;18(11):1180-1184. doi: 10.1111/jch.12845. Epub 2016 Jun 1.PMID: 27251875

 

Adrenal vein sampling versus CT scanning in primary aldosteronism.

Funder JW, Rossi GP.Lancet Diabetes Endocrinol. 2016 Nov;4(11):886. doi: 10.1016/S2213-8587(16)30240-6.PMID: 27793316 No abstract available.

 

Recent advances in the diagnosis and management of obstructive sleep apnea.

Vianello A, Bisogni V, Rinaldo C, Gallan F, Maiolino G, Braccioni F, Guarda-Nardini L, Molena B, Rossi GP, Marchese-Ragona R; Padova Sleep Apnea Study Group.Minerva Med. 2016 Dec;107(6):437-451. Epub 2016 Sep 13.PMID: 27625198 Review.

 

Estrogen Signaling in the Adrenal Cortex: Implications for Blood Pressure Sex Differences.

Caroccia B, Seccia TM, Barton M, Rossi GP.Hypertension. 2016 Oct;68(4):840-8. doi: 10.1161/HYPERTENSIONAHA.116.07660.PMID: 27600178 Review. No abstract available.

 

Metoclopramide unmasks potentially misleading contralateral suppression in patients undergoing adrenal vein sampling for primary aldosteronism.

Rossitto G, Miotto D, Battistel M, Barbiero G, Maiolino G, Bisogni V, Sanga V, Rossi GP.J Hypertens. 2016 Nov;34(11):2258-65. doi: 10.1097/HJH.0000000000001082.PMID: 27512976

 

Obituary: Cesare Dal Palù MD 20-01-1923-18-01-2016.

Pessina AC, Rossi GP.J Hypertens. 2016 May;34(5):1022. doi: 10.1097/hjh.0000000000000900.PMID: 27482560 No abstract available.

 

Endothelin-1 Drives Epithelial-Mesenchymal Transition in Hypertensive Nephroangiosclerosis.

Seccia TM, Caroccia B, Gioco F, Piazza M, Buccella V, Guidolin D, Guerzoni E, Montini B, Petrelli L, Pagnin E, Ravarotto V, Belloni AS, Calò LA, Rossi GP.J Am Heart Assoc. 2016 Jul 21;5(7):e003888. doi: 10.1161/JAHA.116.003888.PMID: 27444511 Free PMC article.

 

Randomised sham-controlled trial of transcutaneous electrical stimulation in obstructive sleep apnoea.

Pengo MF, Xiao S, Ratneswaran C, Reed K, Shah N, Chen T, Douiri A, Hart N, Luo Y, Rafferty GF, Rossi GP, Williams A, Polkey MI, Moxham J, Steier J.Thorax. 2016 Oct;71(10):923-31. doi: 10.1136/thoraxjnl-2016-208691. Epub 2016 Jul 19.PMID: 27435610 Free PMC article. Clinical Trial.

 

Cardiac Remodeling in Patients With Primary and Secondary Aldosteronism: A Tissue Doppler Study.

Cesari M, Letizia C, Angeli P, Sciomer S, Rosi S, Rossi GP.Circ Cardiovasc Imaging. 2016 Jun;9(6):e004815. doi: 10.1161/CIRCIMAGING.116.004815.PMID: 27307552

  News and Events 2024

2024 Winter School in Cardiovascular Medicine

PhD Program Arterial Hypertension and Vascular Biology (ARHYVAB)
University of Padua

The 2023 Winter School of the PhD Course in Arterial Hypertension and Vascular Biology (ARHYVAB), which will take place in Brixen from March 13th to 17th, 2023.

Shaping a World-class University
Brixen, March 4th – 8th, 2024

Venue:
Grüner Baum Hotels, Stufels 11 /Via Stufles 11
39042 Brixen /Bressanone, BZ, Italy

Who can apply
PhD students and Postdocs, members of the EU MINDSHIFT Program, residents in Endocrinology, Internal Medicine, Nephrology and Emergency Medicine, students of the Course in Medicine and other Courses who are interested to the topic are all welcome to apply and participate. Attendance is restricted to 25 people. Fee: 200 euros. No registration fee for the students of the Course in Medicine.


Registration at https://www.sabiwork.it/evento/winter-school/

Deadline for registration: February 28th, 2024

Room reservation. Accomodation can be arranged by yourself. Rooms are available at the Grüner Baum and other hotels, but for a cheaper accommodation you can contact https://www.ostello.bz/it/bressanone.
Scientific contact: teresamaria.seccia@unipd.it
Organizing Secretary: segreteria@sabiwork.it
Deadline for registration: February 28th, 2024